Immune Dysfunction as a Cause and Consequence of Malnutrition

Immune Dysfunction as a Cause and Consequence of Malnutrition

Malnutrition, which encompasses under- and overnutrition, is responsible for an enormous morbidity and mortality burden globally. Malnutrition results from disordered nutrient assimilation but is also characterized by recurrent infections and chronic inflammation, implying an underlying immune defect. Defects emerge before birth via modifications in the immunoepigenome of malnourished parents, ...

Poverty as a cause and consequence of Ill health

Background and aims: Poverty is a multidimensional phenomenon that can be defined in both economic and social terms. The paper attempts to review the existing evidence to understand the relation between poverty and ill health in the context of the limited conceptual and operational definitions of these terms. The paper uses two of Hills criteria- reversibility and dose response relationship to ...

Immune Cell Dysfunction as a Consequence of Severe Sepsis

poverty as a cause and consequence of ill health

background: poverty is a multidimensional phenomenon that can be defined in both economic and social terms. the paper attempts to review existing evidence to understand the relation between poverty and ill health in the context of the limited conceptual and operational definitions of these terms. the paper uses two of hills criteria- reversibility and dose response relationship to understand th...

Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease.

The blood-brain barrier (BBB) plays critical roles in the maintenance of central nervous system (CNS) homeostasis. Dysfunction of the BBB occurs in a number of CNS diseases, including Alzheimer's disease (AD). A prevailing hypothesis in the AD field is the amyloid cascade hypothesis that states that amyloid-β (Aβ) deposition in the CNS initiates a cascade of molecular events that cause neurodeg...